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A novel therapeutic approach for inflammatory bowel disease by exosomes derived from human umbilical cord mesenchymal stem cells to repair intestinal barrier via TSG-6

BACKGROUND: Exosomes as the main therapeutic vectors of mesenchymal stem cells (MSC) for inflammatory bowel disease (IBD) treatment and its mechanism remain unexplored. Tumor necrosis factor-α stimulated gene 6 (TSG-6) is a glycoprotein secreted by MSC with the capacities of tissue repair and immune...

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Detalles Bibliográficos
Autores principales: Yang, Shaopeng, Liang, Xiaonan, Song, Jia, Li, Chenyang, Liu, Airu, Luo, Yuxin, Ma, Heran, Tan, Yi, Zhang, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164818/
https://www.ncbi.nlm.nih.gov/pubmed/34051868
http://dx.doi.org/10.1186/s13287-021-02404-8