Surfactant Assisted Rapid-Release Liposomal Strategies Enhance the Antitumor Efficiency of Bufalin Derivative and Reduce Cardiotoxicity

BACKGROUND: BF211, a derivative of bufalin (BF), shows significantly improved solubility and potent antitumor efficiency compared to BF. Unfortunately, the unwanted toxicity such as cardiotoxicity caused by unspecific distribution has hindered its clinical use. METHODS: PEGylated BF211 liposomes (BF...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Lina, Zhang, Lei, He, Fengjun, Chen, Jing, Zhao, Meng, Li, Simin, Wu, Hao, Liu, Yumeng, Zhang, Yinan, Ping, Qineng, Hu, Lihong, Qiao, Hongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165102/
https://www.ncbi.nlm.nih.gov/pubmed/34079251
http://dx.doi.org/10.2147/IJN.S313153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165102/
https://www.ncbi.nlm.nih.gov/pubmed/34079251
http://dx.doi.org/10.2147/IJN.S313153

Ejemplares similares