KDM2A Targets PFKFB3 for Ubiquitylation to Inhibit the Proliferation and Angiogenesis of Multiple Myeloma Cells

The lysine demethylase KDM2A (also known as JHDM1A or FBXL11) demethylates histone H3 at lysine K36 which lead to epigenetic regulation of cell proliferation and tumorigenesis. However, many biological processes are mediated by KDM2A independently by its histone demethylation activity. In the presen...

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Detalles Bibliográficos
Autores principales: Liu, Xinling, Li, Jiaqiu, Wang, Zhanju, Meng, Jie, Wang, Aihong, Zhao, Xiaofei, Xu, Qilu, Cai, Zhen, Hu, Zhenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165180/
https://www.ncbi.nlm.nih.gov/pubmed/34079757
http://dx.doi.org/10.3389/fonc.2021.653788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165180/
https://www.ncbi.nlm.nih.gov/pubmed/34079757
http://dx.doi.org/10.3389/fonc.2021.653788

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