Histone Deacetylase 5 Is an Early Epigenetic Regulator of Intermittent Hypoxia Induced Sympathetic Nerve Activation and Blood Pressure

Intermittent hypoxia (IH) is a hallmark manifestation of obstructive sleep apnea (OSA). Long term IH (LT-IH) triggers epigenetic reprogramming of the redox state involving DNA hypermethylation in the carotid body chemo reflex pathway resulting in persistent sympathetic activation and hypertension. P...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Peng, Ying-Jie, Su, Xiaoyu, Prabhakar, Nanduri R., Nanduri, Jayasri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165245/
https://www.ncbi.nlm.nih.gov/pubmed/34079475
http://dx.doi.org/10.3389/fphys.2021.688322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165245/
https://www.ncbi.nlm.nih.gov/pubmed/34079475
http://dx.doi.org/10.3389/fphys.2021.688322

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