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Hyperhomocysteinemia exacerbates ischemia-reperfusion injury-induced acute kidney injury by mediating oxidative stress, DNA damage, JNK pathway, and apoptosis

BACKGROUND: Hyperhomocysteinemia (HHcy) plays an important role in the progression of many kidney diseases; however, the relationship between HHcy and ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-induced AKI) is far from clear. In this study, we try to investigate the effect an...

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Detalles Bibliográficos
Autores principales: Zhang, Mei, Yuan, Jing, Dong, Rong, Da, Jingjing, Li, Qian, Hu, Ying, Yu, Fangfang, Ran, Yan, Zha, Yan, Long, Yanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165256/
https://www.ncbi.nlm.nih.gov/pubmed/34124373
http://dx.doi.org/10.1515/biol-2021-0054