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Harmine Alleviates Titanium Particle-Induced Inflammatory Bone Destruction by Immunomodulatory Effect on the Macrophage Polarization and Subsequent Osteogenic Differentiation

Peri-prosthetic osteolysis (PPO) and following aseptic loosening are regarded as the prime reasons for implant failure after joint replacement. Increasing evidence indicated that wear-debris-irritated inflammatory response and macrophage polarization state play essential roles in this osteolytic pro...

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Detalles Bibliográficos
Autores principales: Wang, Liangliang, Wang, Qing, Wang, Wei, Ge, Gaoran, Xu, Nanwei, Zheng, Dong, Jiang, Shijie, Zhao, Gongyin, Xu, Yaozeng, Wang, Yuji, Zhu, Ruixia, Geng, Dechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165263/
https://www.ncbi.nlm.nih.gov/pubmed/34079546
http://dx.doi.org/10.3389/fimmu.2021.657687