Amelioration of Beta Interferon Inhibition by NS4B Contributes to Attenuating Tembusu Virus Virulence in Ducks

Our previous studies reported that duck Tembusu virus nonstructural protein 2A (NS2A) is a major inhibitor of the IFNβ signaling pathway through competitively binding to STING with TBK1, leading to a reduction in TBK1 phosphorylation. Duck TMUV NS2B3 could cleave and bind STING to subvert the IFNβ s...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wei, Zeng, Miao, Jiang, Bowen, Lu, Tong, Guo, Jiaqi, Hu, Tao, Wang, Mingshu, Jia, Renyong, Zhu, Dekang, Liu, Mafeng, Zhao, Xinxin, Yang, Qiao, Wu, Ying, Zhang, Shaqiu, Ou, Xumin, Liu, Yunya, Zhang, Ling, Yu, Yanling, Pan, Leichang, Cheng, Anchun, Chen, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165282/
https://www.ncbi.nlm.nih.gov/pubmed/34079553
http://dx.doi.org/10.3389/fimmu.2021.671471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165282/
https://www.ncbi.nlm.nih.gov/pubmed/34079553
http://dx.doi.org/10.3389/fimmu.2021.671471

Ejemplares similares