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A large-scale investigation into the role of classical HLA loci in multiple types of severe infections, with a focus on overlaps with autoimmune and mental disorders

BACKGROUND: Infections are a major disease burden worldwide. While they are caused by external pathogens, host genetics also plays a part in susceptibility to infections. Past studies have reported diverse associations between human leukocyte antigen (HLA) alleles and infections, but many were limit...

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Detalles Bibliográficos
Autores principales: Nudel, Ron, Allesøe, Rosa Lundbye, Thompson, Wesley K., Werge, Thomas, Rasmussen, Simon, Benros, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165335/
https://www.ncbi.nlm.nih.gov/pubmed/34059071
http://dx.doi.org/10.1186/s12967-021-02888-1