Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease

Pulmonary fibrosis is strongly associated with telomere shortening and increased DNA damage. Key cells in the pathogenesis involve alveolar type 2 (AT2) cells, club cells and myofibroblasts; however, to what extent these cells are affected by telomere shortening and DNA damage is not yet known. We s...

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Detalles Bibliográficos
Autores principales: van Batenburg, Aernoud A., Kazemier, Karin M., van Oosterhout, Matthijs F.M., van der Vis, Joanne J., Grutters, Jan C., Goldschmeding, Roel, van Moorsel, Coline H.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165375/
https://www.ncbi.nlm.nih.gov/pubmed/34084786
http://dx.doi.org/10.1183/23120541.00691-2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165375/
https://www.ncbi.nlm.nih.gov/pubmed/34084786
http://dx.doi.org/10.1183/23120541.00691-2020

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