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The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the Scn1a (+/−) Mouse Model of Dravet Syndrome

Cannabidiol has been approved for the treatment of drug-resistant childhood epilepsies including Dravet syndrome (DS). Although the mechanism of anticonvulsant action of cannabidiol is unknown, emerging data suggests involvement of the transient receptor potential cation channel subfamily V member 1...

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Detalles Bibliográficos
Autores principales: Satpute Janve, Vaishali, Anderson, Lyndsey L., Bahceci, Dilara, Hawkins, Nicole A., Kearney, Jennifer A., Arnold, Jonathon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165383/
https://www.ncbi.nlm.nih.gov/pubmed/34079465
http://dx.doi.org/10.3389/fphar.2021.675128