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Feature Selection Methods for Protein Biomarker Discovery from Proteomics or Multiomics Data

Untargeted mass spectrometry (MS)-based proteomics provides a powerful platform for protein biomarker discovery, but clinical translation depends on the selection of a small number of proteins for downstream verification and validation. Due to the small sample size of typical discovery studies, prot...

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Detalles Bibliográficos
Autores principales: Shi, Zhiao, Wen, Bo, Gao, Qiang, Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165452/
https://www.ncbi.nlm.nih.gov/pubmed/33887487
http://dx.doi.org/10.1016/j.mcpro.2021.100083