A Purified Biflavonoid Extract From Selaginella moellendorffii Alleviates Gout Arthritis via NLRP3/ASC/Caspase-1 Axis Suppression

Background: Activation of nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome plays a crucial role in gout. Selaginella moellendorffii has been confirmed effective for the treatment of gout in hospital preparations. Flavonoids, such as amentoflavone (AM), are the main acti...

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Detalles Bibliográficos
Autores principales: Zhang, Xueyan, Liu, Yingbo, Deng, Guangrui, Huang, Bisheng, Kai, Guoyin, chen, Keli, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165565/
https://www.ncbi.nlm.nih.gov/pubmed/34079466
http://dx.doi.org/10.3389/fphar.2021.676297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165565/
https://www.ncbi.nlm.nih.gov/pubmed/34079466
http://dx.doi.org/10.3389/fphar.2021.676297

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