Extracellular CIRP decreases Siglec-G expression on B-1a cells skewing them towards a pro-inflammatory phenotype in sepsis

BACKGROUND: Sepsis is a life-threatening disease syndrome caused by a dysregulated host response to infection and injury. Extracellular cold-inducible RNA-binding protein (eCIRP) acts as a damage-associated molecular pattern. Peritoneal cavity (PerC) B-1a cells attenuate inflammation and tissue inju...

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Detalles Bibliográficos
Autores principales: Royster, William, Jin, Hui, Wang, Ping, Aziz, Monowar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165807/
https://www.ncbi.nlm.nih.gov/pubmed/34058975
http://dx.doi.org/10.1186/s10020-021-00318-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165807/
https://www.ncbi.nlm.nih.gov/pubmed/34058975
http://dx.doi.org/10.1186/s10020-021-00318-y

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