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A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-κB pathway
BACKGROUND: Multiple myeloma (MM) is a highly aggressive and incurable clonal plasma cell disease with a high rate of recurrence. Thus, the development of new therapies is urgently needed. DCZ0805, a novel compound synthesized from osalmide and pterostilbene, has few observed side effects. In the cu...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165811/ https://www.ncbi.nlm.nih.gov/pubmed/34053438 http://dx.doi.org/10.1186/s12935-021-01973-1 |