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A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-κB pathway

BACKGROUND: Multiple myeloma (MM) is a highly aggressive and incurable clonal plasma cell disease with a high rate of recurrence. Thus, the development of new therapies is urgently needed. DCZ0805, a novel compound synthesized from osalmide and pterostilbene, has few observed side effects. In the cu...

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Detalles Bibliográficos
Autores principales: Gao, Xuejie, Li, Bo, Ye, Anqi, Wang, Houcai, Xie, Yongsheng, Yu, Dandan, Xu, Zhijian, Shi, Bingqing, Zhang, Hui, Feng, Qilin, Hu, Ke, Zhang, Yong, Huang, Cheng, Yang, Guang, Shi, Jumei, Zhu, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165811/
https://www.ncbi.nlm.nih.gov/pubmed/34053438
http://dx.doi.org/10.1186/s12935-021-01973-1