High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma

BACKGROUND: Long-chain acyl-CoA synthetase-4 (ACSL4) is involved in fatty acid metabolism, and aberrant ACSL4 expression could be either tumorigenic or tumor-suppressive in different tumor types. However, the function and clinical significance of ACSL4 in lung adenocarcinoma remain elusive. RESULTS:...

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Detalles Bibliográficos
Autores principales: Zhang, Yixiang, Li, Songyu, Li, Fengzhou, Lv, Changsheng, Yang, Qing-kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166005/
https://www.ncbi.nlm.nih.gov/pubmed/34053456
http://dx.doi.org/10.1186/s13062-021-00294-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166005/
https://www.ncbi.nlm.nih.gov/pubmed/34053456
http://dx.doi.org/10.1186/s13062-021-00294-7

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