Mechanochemical preparation of chrysomycin A self-micelle solid dispersion with improved solubility and enhanced oral bioavailability

BACKGROUND: Chrysomycin A (CA) has been reported as numerous excellent biological activities, such as antineoplastic and antibacterial. Though, poor solubility of CA limited its application in medical field. Due to good amphiphilicity and potential anticancer effect of disodium glycyrrhizin (Na(2)GA...

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Detalles Bibliográficos
Autores principales: Xu, Zhuomin, Zheng, Shanshan, Gao, Xin, Hong, Yulu, Cai, Yue, Zhang, Qiuqin, Xiang, Jiani, Xie, Dehui, Song, Fuxing, Zhang, Huawei, Wang, Hong, Sun, Xuanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166083/
https://www.ncbi.nlm.nih.gov/pubmed/34059070
http://dx.doi.org/10.1186/s12951-021-00911-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166083/
https://www.ncbi.nlm.nih.gov/pubmed/34059070
http://dx.doi.org/10.1186/s12951-021-00911-7

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