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Targeting multiple genes containing long mononucleotide A-T repeats in lung cancer stem cells

BACKGROUND: Intratumour heterogeneous gene expression among cancer and cancer stem cells (CSCs) can cause failure of current targeted therapies because each drug aims to target the function of a single gene. Long mononucleotide A-T repeats are cis-regulatory transcriptional elements that control man...

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Detalles Bibliográficos
Autores principales: Bhummaphan, Narumol, Pin-on, Piyapat, Phiboonchaiyanan, Preeyaporn Plaimee, Siriluksana, Jirattha, Aporntewan, Chatchawit, Chanvorachote, Pithi, Mutirangura, Apiwat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166091/
https://www.ncbi.nlm.nih.gov/pubmed/34059086
http://dx.doi.org/10.1186/s12967-021-02902-6