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On the evolution of chaperones and cochaperones and the expansion of proteomes across the Tree of Life

Across the Tree of Life (ToL), the complexity of proteomes varies widely. Our systematic analysis depicts that from the simplest archaea to mammals, the total number of proteins per proteome expanded ∼200-fold. Individual proteins also became larger, and multidomain proteins expanded ∼50-fold. Apart...

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Detalles Bibliográficos
Autores principales: Rebeaud, Mathieu E., Mallik, Saurav, Goloubinoff, Pierre, Tawfik, Dan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166112/
https://www.ncbi.nlm.nih.gov/pubmed/34001607
http://dx.doi.org/10.1073/pnas.2020885118