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HIV envelope tail truncation confers resistance to SERINC5 restriction

SERINC5 is a potent lentiviral restriction factor that gets incorporated into nascent virions and inhibits viral fusion and infectivity. The envelope glycoprotein (Env) is a key determinant for SERINC restriction, but many aspects of this relationship remain incompletely understood, and the mechanis...

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Detalles Bibliográficos
Autores principales: Haider, Tafhima, Snetkov, Xenia, Jolly, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166163/
https://www.ncbi.nlm.nih.gov/pubmed/34001619
http://dx.doi.org/10.1073/pnas.2101450118