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Ribosome traffic jam in neurodegeneration: decoding hurdles in Huntington disease

A ribosome typically moves at a particular rate on a given mRNA transcript to decode the nucleic acid information required to synthesize proteins. The speed and directionality of the ribosome movements during mRNA translation are determined by the mRNA sequence and structure and by various decoding...

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Detalles Bibliográficos
Autor principal: Subramaniam, Srinivasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166216/
https://www.ncbi.nlm.nih.gov/pubmed/34124583
http://dx.doi.org/10.15698/cst2021.06.251