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miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma

MicroRNAs are a group of endogenous small non-coding RNAs commonly dysregulated in tumorigenesis, including glioblastoma (GBM), the most malignant brain tumor with rapid proliferation, diffuse invasion, and therapeutic resistance. Accumulating evidence has manifested that miR-1258 exerts an inhibito...

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Detalles Bibliográficos
Autores principales: Qin, Hongkun, Gui, Yanping, Ma, Rong, Zhang, Heng, Guo, Yabing, Ye, Yuting, Li, Jia, Zhao, Li, Wang, Yajing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166228/
https://www.ncbi.nlm.nih.gov/pubmed/34079762
http://dx.doi.org/10.3389/fonc.2021.671144