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Cell Adhesion Molecules are Upregulated and May Drive Inflammation in Chronic Rhinosinusitis with Nasal Polyposis

PURPOSE: Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly characterized by eosinophil- and T helper 2 cell (Th2)-biased inflammation. Integrins and intercellular adhesion molecules (ICAMs) are superfamilies of cell adhesion molecules (CAMs) that facilitate the recruitment and traff...

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Detalles Bibliográficos
Autores principales: Blight, Brennan J, Gill, Amarbir S, Sumsion, Jorgen S, Pollard, Chelsea E, Ashby, Shaelene, Oakley, Gretchen M, Alt, Jeremiah A, Pulsipher, Abigail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166329/
https://www.ncbi.nlm.nih.gov/pubmed/34079296
http://dx.doi.org/10.2147/JAA.S307197