Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions

The reader ability of PHD fingers is largely limited to the recognition of the histone H3 N-terminal tail. Distinct subsets of PHDs bind either H3K4me3 (a transcriptional activator mark) or H3K4me0 (a transcriptional repressor state). Structural studies have identified common features among the diff...

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Detalles Bibliográficos
Autores principales: Chen, Jianji, Horton, John, Sagum, Cari, Zhou, Jujun, Cheng, Xiaodong, Bedford, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166343/
https://www.ncbi.nlm.nih.gov/pubmed/33969871
http://dx.doi.org/10.1042/BCJ20210203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166343/
https://www.ncbi.nlm.nih.gov/pubmed/33969871
http://dx.doi.org/10.1042/BCJ20210203

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