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Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions
The reader ability of PHD fingers is largely limited to the recognition of the histone H3 N-terminal tail. Distinct subsets of PHDs bind either H3K4me3 (a transcriptional activator mark) or H3K4me0 (a transcriptional repressor state). Structural studies have identified common features among the diff...
Autores principales: | Chen, Jianji, Horton, John, Sagum, Cari, Zhou, Jujun, Cheng, Xiaodong, Bedford, Mark T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166343/ https://www.ncbi.nlm.nih.gov/pubmed/33969871 http://dx.doi.org/10.1042/BCJ20210203 |
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