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The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols

In vitro (geno)toxicity assessment of electronic vapour products (EVPs), relative to conventional cigarette, currently uses assays, including the micronucleus and Ames tests. Whilst informative on induction of a finite endpoint and relative risk posed by test articles, such assays could benefit from...

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Detalles Bibliográficos
Autores principales: Czekala, Lukasz, Chapman, Fiona, Simms, Liam, Rudd, Kathryn, Trelles Sticken, Edgar, Wieczorek, Roman, Bode, Lisa Maria, Pani, Jutta, Moelijker, Nynke, Derr, Remco, Brandsma, Inger, Hendriks, Giel, Stevenson, Matthew, Walele, Tanvir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166346/
https://www.ncbi.nlm.nih.gov/pubmed/33769537
http://dx.doi.org/10.1093/mutage/geaa033