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Association of APOE Genotype With Heterogeneity of Cognitive Decline Rate in Alzheimer Disease
OBJECTIVE: To test the hypothesis that the APOE genotype is a significant driver of heterogeneity in Alzheimer disease (AD) clinical progression, which could have important implications for clinical trial design and interpretation. METHODS: We applied novel reverse-time longitudinal models to analyz...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Lippincott Williams & Wilkins
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166439/ https://www.ncbi.nlm.nih.gov/pubmed/33771840 http://dx.doi.org/10.1212/WNL.0000000000011883 |