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Association of APOE Genotype With Heterogeneity of Cognitive Decline Rate in Alzheimer Disease

OBJECTIVE: To test the hypothesis that the APOE genotype is a significant driver of heterogeneity in Alzheimer disease (AD) clinical progression, which could have important implications for clinical trial design and interpretation. METHODS: We applied novel reverse-time longitudinal models to analyz...

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Detalles Bibliográficos
Autores principales:	Qian, Jing, Betensky, Rebecca A., Hyman, Bradley T., Serrano-Pozo, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166439/ https://www.ncbi.nlm.nih.gov/pubmed/33771840 http://dx.doi.org/10.1212/WNL.0000000000011883

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