Off-the-Shelf, Immune-Compatible Human Embryonic Stem Cells Generated Via CRISPR-Mediated Genome Editing

Human embryonic stem cells (hESCs) hold promise in regenerative medicine but allogeneic immune rejections caused by highly polymorphic human leukocyte antigens (HLAs) remain a barrier to their clinical applications. Here, we used a CRISPR/Cas9-mediated HLA-editing strategy to generate a variety of H...

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Detalles Bibliográficos
Autores principales: Kim, Annie, Lee, Kun-Gu, Kwon, Yeongbeen, Lee, Kang-In, Yang, Heung-Mo, Habib, Omer, Kim, Jihun, Kim, Sang-Tae, Kim, Sung Joo, Kim, Jin-Soo, Hwang, Dong-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166669/
https://www.ncbi.nlm.nih.gov/pubmed/33423156
http://dx.doi.org/10.1007/s12015-020-10113-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166669/
https://www.ncbi.nlm.nih.gov/pubmed/33423156
http://dx.doi.org/10.1007/s12015-020-10113-7

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