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Spatial and latent memory data in PS2Tg2576 alzheimer's disease mouse model after memantine treatment

We herein present behavioral data on whether memantine, an adamantane derivative and medical NMDA-receptor antagonist, improves spatial and latent learning deficits in amyloid precursor protein/presenilin 2 double-transgenic mice (PS2Tg2576 mice). In PS2Tg2576 mice, early amyloid-β protein (Aβ) depo...

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Detalles Bibliográficos
Autores principales: Matsumura, Masahisa, Sato, Kana, Kubota, Takashi, Kishimoto, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166749/
https://www.ncbi.nlm.nih.gov/pubmed/34095380
http://dx.doi.org/10.1016/j.dib.2021.107131