E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer

Human papillomaviruses (HPV) are a major cause of malignancy worldwide, contributing to ~5% of all human cancers including almost all cases of cervical cancer and a growing number of ano-genital and oral cancers. HPV-induced malignancy is primarily driven by the viral oncogenes, E6 and E7, which man...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Ethan L., Scarth, James A., Patterson, Molly R., Wasson, Christopher W., Hemingway, Georgia C., Barba-Moreno, Diego, Macdonald, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166842/
https://www.ncbi.nlm.nih.gov/pubmed/33303976
http://dx.doi.org/10.1038/s41418-020-00693-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166842/
https://www.ncbi.nlm.nih.gov/pubmed/33303976
http://dx.doi.org/10.1038/s41418-020-00693-9

Ejemplares similares