Cargando…

Targeting STAT3 signaling overcomes gefitinib resistance in non-small cell lung cancer

Lung cancer is one of the most aggressive cancers with poor prognosis and high resistance rate. The family of signal transducer and activator of transcriptions (STATs) appears to modulate resistance in non-small cell lung cancer (NSCLC). In this work, we demonstrated that STAT3/ZEB1 is a critical ax...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Zhe, Ma, Liang, Sun, Yiming, Yu, Wenying, Wang, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166856/
https://www.ncbi.nlm.nih.gov/pubmed/34059647
http://dx.doi.org/10.1038/s41419-021-03844-z