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Role of cytoplasmic localization of maspin in promoting cell invasion in breast cancer with aggressive phenotype

Mammary serine protease inhibitor (maspin) is a tumor suppressor gene that is downregulated during carcinogenesis and breast cancer progression. While the nuclear localization of maspin is essential for tumor suppression, we previously reported that the cytoplasmic localization of maspin was signifi...

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Detalles Bibliográficos
Autores principales: Sakabe, Tomohiko, Wakahara, Makoto, Shiota, Goshi, Umekita, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166868/
https://www.ncbi.nlm.nih.gov/pubmed/34059749
http://dx.doi.org/10.1038/s41598-021-90887-z