C1q/TNF-related protein-9 ameliorates hypoxia-induced pulmonary hypertension by regulating secretion of endothelin-1 and nitric oxide mediated by AMPK in rats

Injury/dysfunction of the endothelium of pulmonary arteries contributes to hypoxia-induced pulmonary hypertension (HPH). We investigated whether C1q/tumor necrosis factor-related protein-9 (CTRP9), a newly identified cardiovascular agent, has protective roles in the development of HPH. HPH was induc...

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Detalles Bibliográficos
Autores principales: Jin, Qiaoyan, Su, Hui, Yang, Rui, Tan, Yanzhen, Li, Buying, Yi, Wei, Dong, Qianqian, Zhang, Haifeng, Xing, Wenjuan, Sun, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166879/
https://www.ncbi.nlm.nih.gov/pubmed/34059748
http://dx.doi.org/10.1038/s41598-021-90779-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166879/
https://www.ncbi.nlm.nih.gov/pubmed/34059748
http://dx.doi.org/10.1038/s41598-021-90779-2

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