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Intestinal α1-2-Fucosylation Contributes to Obesity and Steatohepatitis in Mice

BACKGROUND & AIMS: Fucosyltransferase 2 (Fut2)-mediated intestinal α1- 2-fucosylation is important for host–microbe interactions and has been associated with several diseases, but its role in obesity and hepatic steatohepatitis is not known. The aim of this study was to investigate the role of F...

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Detalles Bibliográficos
Autores principales: Zhou, Rongrong, Llorente, Cristina, Cao, Jinling, Zaramela, Livia S., Zeng, Suling, Gao, Bei, Li, Shang-Zhen, Welch, Ryan D., Huang, Feng-Qing, Qi, Lian-Wen, Pan, Chuyue, Huang, Yan, Zhou, Pengchen, Beussen, Iris, Zhang, Ying, Bryam, Gregory, Fiehn, Oliver, Wang, Lirui, Liu, E-Hu, Yu, Ruth T., Downes, Michael, Evans, Ronald M., Goglin, Karrie, Fouts, Derrick E., Brenner, David A., Bode, Lars, Fan, Xuegong, Zengler, Karsten, Schnabl, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166943/
https://www.ncbi.nlm.nih.gov/pubmed/33631374
http://dx.doi.org/10.1016/j.jcmgh.2021.02.009