B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling

Modulation of T-cell responses has played a key role in treating cancers and autoimmune diseases. Therefore, understanding how different receptors on T cells impact functional outcomes is crucial. The influence of B7-H7 (HHLA2) and CD28H (TMIGD2) on T-cell activation remains controversial. Here we e...

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Detalles Bibliográficos
Autores principales: Rieder, Sadiye Amcaoglu, Wang, Jingya, White, Natalie, Qadri, Ariful, Menard, Catherine, Stephens, Geoffrey, Karnell, Jodi L., Rudd, Christopher E., Kolbeck, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166953/
https://www.ncbi.nlm.nih.gov/pubmed/32005952
http://dx.doi.org/10.1038/s41423-020-0361-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166953/
https://www.ncbi.nlm.nih.gov/pubmed/32005952
http://dx.doi.org/10.1038/s41423-020-0361-7

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