Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons

ALS is characterized by progressive inability to execute movements. Motor neurons innervating fast-twitch muscle-fibers preferentially degenerate. The reason for this differential vulnerability and its consequences on motor output is not known. Here, we uncover that fast motor neurons receive strong...

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Detalles Bibliográficos
Autores principales: Allodi, Ilary, Montañana-Rosell, Roser, Selvan, Raghavendra, Löw, Peter, Kiehn, Ole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166981/
https://www.ncbi.nlm.nih.gov/pubmed/34059686
http://dx.doi.org/10.1038/s41467-021-23224-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166981/
https://www.ncbi.nlm.nih.gov/pubmed/34059686
http://dx.doi.org/10.1038/s41467-021-23224-7

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