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Semi-Automated Glycoproteomic Data Analysis of LC-MS Data Using GlycopeptideGraphMS in Process Development of Monoclonal Antibody Biologics

The glycosylation of antibody-based proteins is vital in translating the right therapeutic outcomes of the patient. Despite this, significant infrastructure is required to analyse biologic glycosylation in various unit operations from biologic development, process development to QA/QC in bio-manufac...

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Detalles Bibliográficos
Autores principales: Pang, Kuin Tian, Tay, Shi Jie, Wan, Corrine, Walsh, Ian, Choo, Matthew S. F., Yang, Yuan Sheng, Choo, Andre, Ho, Ying Swan, Nguyen-Khuong, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167043/
https://www.ncbi.nlm.nih.gov/pubmed/34084765
http://dx.doi.org/10.3389/fchem.2021.661406