Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response

Monomethyl fumarate (MMF), metabolite of dimethyl fumarate (DMF), an immunosuppressive drug approved for the treatment of multiple sclerosis (MS), is a potent agonist for hydroxycarboxylic acid receptor 2 (HCAR2), eliciting signals that dampen cell activation or lead to inflammation such as the skin...

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Detalles Bibliográficos
Autores principales: Parodi, Benedetta, Sanna, Alessia, Cedola, Alessia, Uccelli, Antonio, Kerlero de Rosbo, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167049/
https://www.ncbi.nlm.nih.gov/pubmed/34084164
http://dx.doi.org/10.3389/fimmu.2021.655212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167049/
https://www.ncbi.nlm.nih.gov/pubmed/34084164
http://dx.doi.org/10.3389/fimmu.2021.655212

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