Kdm6a suppresses the alternative activation of macrophages and impairs energy expenditure in obesity

Histone lysine demethylase 6a (Kdm6a) mediates the removal of repressive trimethylation from histone H3 lysine 27 (H3K27me3) to activate target gene expression. Obesity is associated with metabolic inflammation, and adipose tissue macrophages (ATMs) are key players orchestrating metabolic inflammati...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jun, Xu, Xing, Li, Yan, Li, Fan, Zhang, Jianjun, Xu, Qin, Chen, Wantao, Wei, Yan, Wang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167088/
https://www.ncbi.nlm.nih.gov/pubmed/33303977
http://dx.doi.org/10.1038/s41418-020-00694-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167088/
https://www.ncbi.nlm.nih.gov/pubmed/33303977
http://dx.doi.org/10.1038/s41418-020-00694-8

Ejemplares similares