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Ferroptotic pores induce Ca(2+) fluxes and ESCRT-III activation to modulate cell death kinetics

Ferroptosis is an iron-dependent form of regulated necrosis associated with lipid peroxidation. Despite its key role in the inflammatory outcome of ferroptosis, little is known about the molecular events leading to the disruption of the plasma membrane during this type of cell death. Here we show th...

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Detalles Bibliográficos
Autores principales: Pedrera, Lohans, Espiritu, Rafael A., Ros, Uris, Weber, Josephine, Schmitt, Anja, Stroh, Jenny, Hailfinger, Stephan, von Karstedt, Silvia, García-Sáez, Ana J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167089/
https://www.ncbi.nlm.nih.gov/pubmed/33335287
http://dx.doi.org/10.1038/s41418-020-00691-x