WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

WDR62 is a scaffold protein involved in centriole duplication and spindle assembly during mitosis. Mutations in WDR62 can cause primary microcephaly and premature ovarian insufficiency. We have generated a genetrap mouse model deficient in WDR62 and characterised the developmental effects of WDR62 d...

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Detalles Bibliográficos
Autores principales: Ho, Uda Y., Feng, Chun-Wei Allen, Yeap, Yvonne Y., Bain, Amanda L., Wei, Zhe, Shohayeb, Belal, Reichelt, Melissa E., Homer, Hayden, Khanna, Kum Kum, Bowles, Josephine, Ng, Dominic C. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167107/
https://www.ncbi.nlm.nih.gov/pubmed/34059773
http://dx.doi.org/10.1038/s42003-021-02171-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167107/
https://www.ncbi.nlm.nih.gov/pubmed/34059773
http://dx.doi.org/10.1038/s42003-021-02171-5

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