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Prostate cancer risk variants of the HOXB genetic locus

The G84E germline mutation of HOXB13 predisposes to prostate cancer and is clinically tested for familial cancer care. We investigated the HOXB locus to define a potentially broader contribution to prostate cancer heritability. We sought HOXB locus germline variants altering prostate cancer risk in...

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Detalles Bibliográficos
Autores principales: Dupont, William D., Breyer, Joan P., Johnson, Spenser H., Plummer, W. Dale, Smith, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167119/
https://www.ncbi.nlm.nih.gov/pubmed/34059701
http://dx.doi.org/10.1038/s41598-021-89399-7