High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol

Autophagy is an intracellular recycling pathway with implications for intracellular homeostasis and cell survival. Its pharmacological modulation can aid chemotherapy by sensitizing cancer cells toward approved drugs and overcoming chemoresistance. Recent translational data on autophagy modulators s...

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Detalles Bibliográficos
Autores principales: Deitersen, Jana, Berning, Lena, Stuhldreier, Fabian, Ceccacci, Sara, Schlütermann, David, Friedrich, Annabelle, Wu, Wenxian, Sun, Yadong, Böhler, Philip, Berleth, Niklas, Mendiburo, María José, Seggewiß, Sabine, Anand, Ruchika, Reichert, Andreas S., Monti, Maria Chiara, Proksch, Peter, Stork, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167120/
https://www.ncbi.nlm.nih.gov/pubmed/34059630
http://dx.doi.org/10.1038/s41419-021-03830-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167120/
https://www.ncbi.nlm.nih.gov/pubmed/34059630
http://dx.doi.org/10.1038/s41419-021-03830-5

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