Inflammation-induced inhibition of chaperone-mediated autophagy maintains the immunosuppressive function of murine mesenchymal stromal cells

Macroautophagy has been implicated in modulating the therapeutic function of mesenchymal stromal cells (MSCs). However, the biological function of chaperone-mediated autophagy (CMA) in MSCs remains elusive. Here, we found that CMA was inhibited in MSCs in response to the proinflammatory cytokines in...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Huang, Jiefang, Gu, Yuting, Xue, Mingxing, Qian, Fengtao, Wang, Bei, Yang, Wanlin, Yu, Hongshuang, Wang, Qiwei, Guo, Xin, Ding, Xinyuan, Wang, Jina, Jin, Min, Zhang, Yanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167126/
https://www.ncbi.nlm.nih.gov/pubmed/31900460
http://dx.doi.org/10.1038/s41423-019-0345-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167126/
https://www.ncbi.nlm.nih.gov/pubmed/31900460
http://dx.doi.org/10.1038/s41423-019-0345-7

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