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Improved cardiac-specific delivery of RAGE siRNA within small extracellular vesicles engineered to express intense cardiac targeting peptide attenuates myocarditis

Small extracellular vesicles (sEVs) are nanometer-sized membranous vesicles secreted by cells, with important roles in physiological and pathological processes. Recent research has established the application of sEVs as therapeutic vehicles in various conditions, including heart disease. However, th...

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Detalles Bibliográficos
Autores principales: Kim, Hyoeun, Mun, Dasom, Kang, Ji-Young, Lee, Seung-Hyun, Yun, Nuri, Joung, Boyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167198/
https://www.ncbi.nlm.nih.gov/pubmed/34141457
http://dx.doi.org/10.1016/j.omtn.2021.04.018