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Chemical Characterization and Quantification of Circulating Intact PTH and PTH Fragments by High-Resolution Mass Spectrometry in Chronic Renal Failure

BACKGROUND: The precise concentrations of full-length parathyroid hormone (PTH1-84) and the identity and concentrations of PTH fragments in patients with various stages of chronic renal failure are unknown. METHODS: We developed a liquid chromatography-high resolution mass spectrometry (LC-HRMS) met...

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Detalles Bibliográficos
Autores principales: Kritmetapak, Kittrawee, Losbanos, Louis A, Hines, Jolaine M, O’Grady, Katherine L, Ulmer, Candice Z, Vesper, Hubert W, Enders, Felicity T, Singh, Ravinder J, Kumar, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167341/
https://www.ncbi.nlm.nih.gov/pubmed/33693557
http://dx.doi.org/10.1093/clinchem/hvab013