Poly(U)‐specific endoribonuclease ENDOU promotes translation of human CHOP mRNA by releasing uORF element‐mediated inhibition

Upstream open reading frames (uORFs) are known to negatively affect translation of the downstream ORF. The regulatory proteins involved in relieving this inhibition are however poorly characterized. In response to cellular stress, eIF2α phosphorylation leads to an inhibition of global protein synthe...

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Detalles Bibliográficos
Autores principales: Lee, Hung‐Chieh, Fu, Chuan‐Yang, Lin, Cheng‐Yung, Hu, Jia‐Rung, Huang, Ting‐Ying, Lo, Kai‐Yin, Tsai, Hsin‐Yue, Sheu, Jin‐Chuan, Tsai, Huai‐Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167367/
https://www.ncbi.nlm.nih.gov/pubmed/33511665
http://dx.doi.org/10.15252/embj.2019104123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167367/
https://www.ncbi.nlm.nih.gov/pubmed/33511665
http://dx.doi.org/10.15252/embj.2019104123

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