Cargando…

Poly(U)‐specific endoribonuclease ENDOU promotes translation of human CHOP mRNA by releasing uORF element‐mediated inhibition

Upstream open reading frames (uORFs) are known to negatively affect translation of the downstream ORF. The regulatory proteins involved in relieving this inhibition are however poorly characterized. In response to cellular stress, eIF2α phosphorylation leads to an inhibition of global protein synthe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Hung‐Chieh, Fu, Chuan‐Yang, Lin, Cheng‐Yung, Hu, Jia‐Rung, Huang, Ting‐Ying, Lo, Kai‐Yin, Tsai, Hsin‐Yue, Sheu, Jin‐Chuan, Tsai, Huai‐Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167367/ https://www.ncbi.nlm.nih.gov/pubmed/33511665 http://dx.doi.org/10.15252/embj.2019104123

Ejemplares similares

Embryonic expression patterns of Eukaryotic EndoU ribonuclease family gene endouC in zebrafish
por: Lee, Hung-Chieh, et al.
Publicado: (2017)

Ribo-uORF: a comprehensive data resource of upstream open reading frames (uORFs) based on ribosome profiling
por: Liu, Qi, et al.
Publicado: (2022)

Loss-of-function uORF mutations in human malignancies
por: Schulz, Julia, et al.
Publicado: (2018)

uORFs: Important Cis-Regulatory Elements in Plants
por: Zhang, Ting, et al.
Publicado: (2020)

uORFdb—a comprehensive literature database on eukaryotic uORF biology
por: Wethmar, Klaus, et al.
Publicado: (2014)

The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD)
por: Stockklausner, Clemens, et al.
Publicado: (2006)

hnRNPs and ELAVL1 cooperate with uORFs to inhibit protein translation
por: Zhang, Jiewen, et al.
Publicado: (2017)

Impacts of uORF codon identity and position on translation regulation
por: Lin, Yizhu, et al.
Publicado: (2019)

Determinants of genome-wide distribution and evolution of uORFs in eukaryotes
por: Zhang, Hong, et al.
Publicado: (2021)

Impact of uORFs in mediating regulation of translation in stress conditions
por: Moro, Simone G., et al.
Publicado: (2021)

Translational regulation by uORFs and start codon selection stringency
por: Dever, Thomas E., et al.
Publicado: (2023)

The Emerging Role of uORF-Encoded uPeptides and HLA uLigands in Cellular and Tumor Biology
por: Jürgens, Lara, et al.
Publicado: (2022)

Functional plasticity of antibacterial EndoU toxins
por: Michalska, Karolina, et al.
Publicado: (2018)

Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish
por: Chew, Guo-Liang, et al.
Publicado: (2016)

Author Correction: Loss-of-function uORF mutations in human malignancies
por: Schulz, Julia, et al.
Publicado: (2021)

uORFlight: a vehicle toward uORF-mediated translational regulation mechanisms in eukaryotes
por: Niu, Ruixia, et al.
Publicado: (2020)

uORF4u: a tool for annotation of conserved upstream open reading frames
por: Egorov, Artyom A, et al.
Publicado: (2023)

Author Correction: Determinants of genome-wide distribution and evolution of uORFs in eukaryotes
por: Zhang, Hong, et al.
Publicado: (2021)

A natural uORF variant confers phosphorus acquisition diversity in soybean
por: Guo, Zilong, et al.
Publicado: (2022)

Evolutionarily conserved inhibitory uORFs sensitize Hox mRNA translation to start codon selection stringency
por: Ivanov, Ivaylo P., et al.
Publicado: (2022)

A conserved uORF in the ilvBNC mRNA of Corynebacterium species regulates ilv operon expression
por: Narunsky, Aya, et al.
Publicado: (2023)

Fail-safe mechanism of GCN4 translational control—uORF2 promotes reinitiation by analogous mechanism to uORF1 and thus secures its key role in GCN4 expression
por: Gunišová, Stanislava, et al.
Publicado: (2014)

The new uORFdb: integrating literature, sequence, and variation data in a central hub for uORF research
por: Manske, Felix, et al.
Publicado: (2022)

Complexity and Conservation of Thermospermine-Responsive uORFs of SAC51 Family Genes in Angiosperms
por: Ishitsuka, Soichi, et al.
Publicado: (2019)

uORF Shuffling Fine-Tunes Gene Expression at a Deep Level of the Process
por: Kurihara, Yukio
Publicado: (2020)

uORF-Tools—Workflow for the determination of translation-regulatory upstream open reading frames
por: Scholz, Anica, et al.
Publicado: (2019)

Annotation of uORFs in the OMIM genes allows to reveal pathogenic variants in 5′UTRs
por: Filatova, Alexandra, et al.
Publicado: (2023)

Making Use of Plant uORFs to Control Transgene Translation in Response to Pathogen Attack
por: Ai, Gan, et al.
Publicado: (2022)

DAP5 enables main ORF translation on mRNAs with structured and uORF-containing 5′ leaders
por: Weber, Ramona, et al.
Publicado: (2022)

An ancient evolutionary connection between Ribonuclease A and EndoU families
por: Mushegian, Arcady, et al.
Publicado: (2020)

Physiologic RNA targets and refined sequence specificity of coronavirus EndoU
por: Ancar, Rachel, et al.
Publicado: (2020)

DENR•MCT-1 Promotes Translation Reinitiation Downstream of uORFs to Control Tissue Growth
por: Schleich, Sibylle, et al.
Publicado: (2014)

uORF-mediated translation allows engineered plant disease resistance without fitness costs
por: Xu, Guoyong, et al.
Publicado: (2017)

Application of Upstream Open Reading Frames (uORFs) Editing for the Development of Stress-Tolerant Crops
por: Um, Taeyoung, et al.
Publicado: (2021)

Unraveling the hidden role of a uORF-encoded peptide as a kinase inhibitor of PKCs
por: Jayaram, Divya Ram, et al.
Publicado: (2021)

Conserved non-AUG uORFs revealed by a novel regression analysis of ribosome profiling data
por: Spealman, Pieter, et al.
Publicado: (2018)

Ribosomal leaky scanning through a translated uORF requires eIF4G2
por: Smirnova, Victoria V, et al.
Publicado: (2022)

An epitope encoded by uORF of RNF10 elicits a therapeutic anti-tumor immune response
por: Zeng, Lili, et al.
Publicado: (2023)

Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting
por: Fritsch, Claudia, et al.
Publicado: (2012)

Rules of UGA-N decoding by near-cognate tRNAs and analysis of readthrough on short uORFs in yeast
por: Beznosková, Petra, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bj76l20847r71o5pj061onacds