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Bioactive α-Pyrone Derivatives from the Endophytic Fungus Diaporthe sp. CB10100 as Inducible Nitric Oxide Synthase Inhibitors

Inducible nitric oxide synthase (iNOS) produces NO from l-arginine and plays critical roles in inflammation and immune activation. Selective and potent iNOS inhibitors may be potentially used in many indications, such as rheumatoid arthritis, pain, and neurodegeration. In the current study, five new...

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Detalles Bibliográficos
Autores principales: Pu, Hong, Liu, Jianxin, Wang, Yeji, Peng, Yuhui, Zheng, Wanying, Tang, Yang, Hui, Boping, Nie, Chunmei, Huang, Xueshuang, Duan, Yanwen, Huang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167431/
https://www.ncbi.nlm.nih.gov/pubmed/34084766
http://dx.doi.org/10.3389/fchem.2021.679592